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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRSK2 All Species: 11.52
Human Site: T447 Identified Species: 28.15
UniProt: Q8IWQ3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWQ3 NP_003948.2 736 81633 T447 P L P T P K G T P V H T P K E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850919 676 75195 T387 P L P T P K G T P V H T P K E
Cat Felis silvestris
Mouse Mus musculus Q69Z98 735 81715 T448 P L P T P K G T P V H T P K E
Rat Rattus norvegicus Q8VHF0 797 88733 S489 D I P E R K K S P A V P S S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IA88 798 88848 P467 Y D H P I R I P S N T S R R H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 P756 Q S P S D S P P P T S L P R M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648814 861 95238 S563 F H D P D S N S V V N P N G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 N725 T M M S K L I N K T P A A G G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 K228 E N I P N L F K K I K G G I Y
Baker's Yeast Sacchar. cerevisiae P34244 1518 169574 P620 T V H D N E M P L P Q L P K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 89.8 N.A. 97.9 25.4 N.A. N.A. 27.4 N.A. 25.1 N.A. 50.9 N.A. 23.1 N.A.
Protein Similarity: 100 N.A. N.A. 90.3 N.A. 98.7 43.2 N.A. N.A. 43.9 N.A. 37.9 N.A. 63.5 N.A. 37.3 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 20 N.A. N.A. 0 N.A. 20 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 33.3 N.A. N.A. 20 N.A. 33.3 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.8 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 33.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 10 10 20 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 30 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 30 0 0 0 0 10 10 20 10 % G
% His: 0 10 20 0 0 0 0 0 0 0 30 0 0 0 10 % H
% Ile: 0 10 10 0 10 0 20 0 0 10 0 0 0 10 0 % I
% Lys: 0 0 0 0 10 40 10 10 20 0 10 0 0 40 0 % K
% Leu: 0 30 0 0 0 20 0 0 10 0 0 20 0 0 0 % L
% Met: 0 10 10 0 0 0 10 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 20 0 10 10 0 10 10 0 10 0 10 % N
% Pro: 30 0 50 30 30 0 10 30 50 10 10 20 50 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 10 10 0 0 0 0 0 0 10 20 0 % R
% Ser: 0 10 0 20 0 20 0 20 10 0 10 10 10 10 20 % S
% Thr: 20 0 0 30 0 0 0 30 0 20 10 30 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 10 40 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _